cannabis and cbd

cannabis and cbd

Postby holy vehm » Mon Mar 14, 2011 6:41 pm

There are a couple of threads on here regards cannabis but mainly about the 'right' to consume.

I would like to discuss the chemical CBD that is naturally found in the cannabis plant.
Most growers pursue higher THC levels at the expense of CBD, it is CBD that gives the plant its medicinal properties. To much THC and you get the strong high but less of the medicinal properties and a low THC level gives you a much lower 'high' with more medicinal properties.

Also, what is it that actually makes cannabis illegal, is it the thc levels (the high) or does it not matter.
It would seem to me that if you received no high or a low one and used the plant for its medicinal properties then why should people be criminalised.

A few links to go through.

http://en.wikipedia.org/wiki/Cannabidiol

http://www.telegraph.co.uk/health/8080247/The-rise-of-high-CBD-marijuana-Cannabis.html

http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

I have often wondered if tptb are responsible for the cannabis of choice, skunk or homegrown. This is very strong, thc rich weed, are they (tptb) aware that in the past, that smokers who smoked a more natural weed were actually healthier due to the higher levels of cbd and in turn 'allowed' what is consumed today.

The question, i suppose, is, is there a government backed suppression of CBD?

Now im no expert on this, i came across it and found it of interest and thought i would share (freemen only chat) with those who have an interest in such things.
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Re: cannabis and cbd

Postby enegiss » Mon Mar 14, 2011 6:58 pm

check this out HV, gives ya an idea of the depth of things
http://www.cannabisfarmer.com/web/node/39
peace and light. met him in london couple or three years ago at a hemp expo, ex smuggler, associated i believe with the brotherhood of love, :grin: nice guy
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Re: cannabis and cbd

Postby holy vehm » Mon Dec 26, 2011 4:16 pm

Cannabis may help keep Alzheimer's disease at bay.

In experiments, a marijuana-based medicine triggered the formation of new brain cells and cut inflammation linked to dementia.

The researchers say that using the information to create a pill suitable for people could help prevent or delay the onset of Alzheimer's.

The incurable disease affects 400,000 Britons, with around 500 new cases diagnosed every day as people live longer.

For some sufferers, drugs can delay the progress of devastating symptoms such as memory loss and the erosion of ability to do everyday things such as washing.

However, there they do not work for everyone and, with the number of patients forecast to double in a generation, there is a desperate need for new treatments.

The US researchers studied the properties of a man-made drug based on THC, the chemical behind the 'high' of cannabis.

When elderly rats were given the drug for three weeks, it improved their memory, making it easier for them to find their way round a water maze, the Society for Neuroscience's annual conference heard yesterday (WEDS).

Researcher Dr Yannick Marchalant said; 'Old rats are not very good at that task. When we gave them the drug, it made them a little better at that task.'

Other experiments showed that the drug acts on parts of the brain involved in memory, appetite, pain and mood.

The Ohio State University experiments also showed that the drug cut inflammation in the brain and may trigger the production of new neurons or brain cells.

Researcher Professor Gary Wenk said: 'When we're young, we produce neurons and our memory works fine.

'When we age, the process slows down, so we have a decrease in new cell formation through normal ageing.

'You need these cells to come back and help form new memories and we found that this THC-like agent can influence the creation of these cells.'

Although the drug used was not suitable for use in people, the results could aid the creation of new medicines for Alzheimer's.

It is likely such a drug would be taken to prevent the disease, rather than treat it.

Asked if those with a family history of Alzheimer's should smoke cannabis to prevent them developing the disease, Dr Wenk said: 'We're not saying that but it might actually work.

'What we are saying its that it appears that a safe, legal substance that mimics the important properties of marijuana can work on the brain to prevent memory impairments in ageing. So that's really hopeful.'

Dr Marchalant added: 'We hope a compound can be found that can target both inflammation and neurogenesis, which would be the most efficient way to produce the best effects.'

The medicinal properties of cannabis have already been harnessed to treat multiple sclerosis.

Sativex, a cannabis-based drug, has been shown to ease the symptoms of multiple sclerosis, including pain, spasms, shaking, depression and anxiety.

The Alzheimer's Society cautioned against using cannabis itself to stave off dementia.

Professor Clive Ballard, the charity's director of research, said: 'There are encouraging findings from studies with animals suggesting that some cannabis derivatives may help protect nerve cells in the brain.

'We therefore look forward to robust clinical trials into potential benefits of non-psychoactive components of cannabis.

'It is important for people to note that these treatments are not same as recreational cannabis use which can be potentially harmful.'


http://www.dailymail.co.uk/health/article-1087544/Cannabis-stop-dementia-tracks.html

Although this may be a 'good' news story it is worth remembering that a high thc and low cbd weed is actually detrimental, find or grow a good natural (as nature intended) supply and stick with it. Do not smoke that fucked up skunk weed shyte, that stuff is not how nature intended.
A good natural weed smells sweet, much like chocolate orange while skunk stinks like cat piss.
If you grow your own ensure just before you harvest the crop that you flush it through with spring water. This area is often one which actually leaves the weed contaminated, people using either tap water (flouride) or any number of these new products to flush them through.
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Re: cannabis and cbd

Postby enegiss » Mon Dec 26, 2011 6:38 pm

i think the breeding of the high THC aspect was down to the DEA, in a way to gain the plant for only medical prescibed purposes, and they seem to be on their way with the DEA licenced, G W pharmaceutics company. this is on the link i posted above.
A bit of history:
At a 1997 Vancouver Hemp conference, Watson spoke of his research. His main focus was to stop growers from cloning nor being able to create any seeds, from strains being bred in Amsterdam. The funding for this research came partially from the Dutch Government, the rest from DEA. Watson had been busted for growing in Santa Cruz California 3-20-85 and resurfaced in Amsterdam to start his seed company Cultivator’s Choice. DEA supported the Skunkman’s application for a license to grow for research in Holland, even though they should have been extraditing him back to Cali for his 1985 in Santa Cruz grow bust! DEA endorsement was so strong that he was the first to be granted a permit in Holland when several universities and domestic research groups with PHD’s and legitimate reasons for research were denied! The Dutch government even supplied three greenhouses for Dr. Frankenbeanstein to do his heinous experiments, while normal Dutch growers lost all their equipment and had to serve murder-like sentences at that time! Dutch seed companies have become the Monsanto of the cannabis seed industry, and hope to make us all seed junkies at $20 a seed.!

The license gave Hortapharm/Skunkman/DEA control over what researchers are allowed access to pedigreed seeds of predictable quality! The object is to patent up every possible combination of cannabinoids and terpenes with efficacy for every possible disease they can treat, and every possible genetic sequence! Once ready to make the move, they will shut down every medical cannabis grower for patent fraud, and those they can’t will be run out when they produce a more effective product for significantly less than $250 an ounce the growers are getting! The Skunkman’s company Hortapharm, is the only private organization approved by the Drug Enforcement Agency to supply genetics to researchers to this day!

Gibberillen is a natural g
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Re: cannabis and cbd

Postby holy vehm » Tue Dec 27, 2011 8:58 am

That is an interesting quote mate and kinda answers the original question (is cbd being surpressed by tptb)

Also of interests and linked is the fact that the dutch authorities plan to ban the sale of cannabis to non dutch nationals, could this be an experiment on the dutch populace?
By only allowing a certain section to use the new GM variety that can closer examine the effects before rolling it out to the wider world.
I wonder if they plan to make the natural varities illegal and the GM legal. It would be interesting to see the levels of thc and cbd in these new strains they have planned.

The world will consume useless cannabis while paying taxation with no health benefits. The health benefits will have been patented by big pharma and will not be allowed to be grown for personal usage without a licence.

Many years back a couple of growers i know were into the mexican variety, always got a good crop but they couldnt compete with the skunk so gave up. People think stronger is better and most wont be told anything differant.

Start collecting seeds me thinks, and start a seed bank before its to late.
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Re: cannabis and cbd

Postby enegiss » Fri Dec 30, 2011 2:04 pm

High quality global journalism requires investment. Please share this article with others using the link below, do cut & paste the article. See our Ts&Cs and Copyright Policy for more detail. Email ftsales.support@ft.com to buy additional rights. http://www.ft.com/cms/s/0/299baa7e-27df-11e1-9433-00144feabdc0.html#ixzz1i1iI51NK

GW Pharmaceuticals aims to build on cannabis drug
By Mark Wembridge
There are few entities that can publicly boast that they grow 20 tonnes of cannabis a year with government approval. GW Pharmaceuticals, however, is one of them.
The crop’s Home Office-approved location is shrouded in mystery, with the only hint from GW being that it is “somewhere in the south” of the UK.
More

ON THIS STORY
GW cultivates market for MS cannabis drug
Novartis to sell medical marijuana
GW Pharmaceuticals gets boost from Sativex
IN PHARMACEUTICALS
Abbott to finalise name change
Shire in warning on drug pricing
J&J opts out of HIV rights sharing pool
Ranbaxy makes $500m provision on FDA deal
From a plant better known for its illicit use, the British biotech group created the drug Sativex, an oral spray medication used to ease spasticity in multiple sclerosis patients, which is available on prescription in New Zealand, Canada, Spain, Germany and the UK, and has recently been approved in Sweden.
Sativex, launched in the UK in June, is the only cannabis-based medicine to receive approval from medical authorities for use as a prescription drug, and has been the driving force behind Aim-traded GW.
However, Justin Gover, managing director, believes that the drug is only the first of several that the company will bring to the market.
“We have done this for Sativex and there is no reason why we can’t do it for three or four more,” he says in an interview with the Financial Times. “All our medicines are cousins – they all come from the same plant and are therefore very similar.”
Mr Gover believes that the active molecules found in cannabis, known as cannabinoids, can be used to treat conditions including diabetes, high cholesterol, liver problems and even cancer itself.
The group has spent £5m of its own cash in developing treatments for what Mr Gover calls “metabolic syndrome” – or the effects of modern diets and lifestyles on our health.
“It is part of taking the company from being a young drug development company with a focus on a lead product to expand into other areas,” he says.
“We have two major ambitions for us. The first is to maximise the opportunities of Sativex itself . . . and the second is to realise value from the use of cannabinoid’s across multiple therapeutic areas. And that’s our competitive and strategic position in the industry.”
GW’s trials of an oral capsule to treat type two diabetes is in the second stage of clinical trials. It has signed two deals worth a total of $21m with Otsuka, the Japanese drug group, on pre-clinical testing of cannabinoid’s to treat epilepsy, as well as various cancers including prostate, breast and glioma (brain cancer).
The company is also working with Otsuka to test Sativex for relief of pain caused by illnesses including cancer, in a market that is estimated to be worth $1.7bn (£1bn) a year in the US alone.
Earlier this year, GW signed a £20.7m distribution deal for Sativex with Novartis for some emerging markets – a deal that includes milestone payments for GW of $34m, conditional on winning regulatory approval and other hurdles, and double-digit royalties – to complement existing alliances with Almirall and Bayer.
“This is the next opportunity for us – to take the same drug and get it approved for a different use,” Mr Gover says.
As GW’s medicines come from cannabis – a natural product – instead of a synthetic compound, intellectual property rights on the drug are limited, extracting the cannabinoids in the manufacturing process is complex, and Home Office regulatory approval is difficult.
However, the complexity of creating its drugs is also a deterrent to possible generic rivals, Mr Gover says. “Our area requires a new expertise for generic drug companies to reproduce these medicines, so we’re not overly concerned with them.”
The approval of Sativex and GW’s expansion into other drugs comes after a lean spell that it endured from 2004-07, when its shares dropped from above 200p to below 30p, after a spate of trials failed to show convincingly that cannabis-based products could relieve pain. The shares stood at 81.50p in late trading on Wednesday.
However, the eventual launch of Sativex and its financial boost to GW has enabled the company to further investigate the medical possibilities for cannabis, Mr Gover says.
“If we can continue to demonstrate that cannabinoid’s – these fascinating molecules that sit within the cannabis plant – have these range of applications and opportunities, we can harness our position in the industry to stay as leaders in this field.” And they steal my child for working in Kashmir doing the same thing, fucking Criminals the lot of em
http://pr.cannazine.co.uk/201112171549/green/eco-news/gw-pharma-cannabis-monopoly-questioned-by-clear-uk.html
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